Uneventful course in patients with inflammatory bowel disease during the severe acute respiratory syndrome coronavirus 2 outbreak in Northern Italy
Date
2020Author
Norsa, Lorenzo
Indriolo, Amedeo
Sansotta, Naire
Cosimo, Paola
Greco, Salvatore
D’Antiga, Lorenzo
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Abstract
Since December 2019, the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) responsible
for coronavirus disease 2019 (COVID-19) has caused a
pandemic, with more than 350,000 cases and more than
15,000 fatalities reported worldwide so far (https://www.
healthmap.org/covid-19/). The first case series from the
Wuhan population, describing the clinical characteristics of
the SARS-CoV-2 infection in China, were recently published.1
However, further evidence is required to predict who is at
higher risk of developing clinical symptoms.
After the outbreak in China, the Lombardy region in Italy
has become one of the areas with the highest incidence of
new cases, and the outbreak is estimated to have begun on
February 18, 2020. In particular, the province of Bergamo
has reported, to date, 6471 positive results on nasopharyngeal swab for SARS-CoV-2 in a population of 1,114,590 inhabitants and is, therefore, the province with the highest rate
of infection per 100,000 inhabitants worldwide2 (http://
www.salute.gov.it/portale/nuovocoronavirus/). A recent
publication by the IBD Elite Union, which incorporates the 7
largest inflammatory bowel disease (IBD) referral centers in
China, with more than 20,000 patients with IBD, reported no
cases of COVID-19. This report included the 3 largest tertiary
IBD centers in Wuhan (Tongji Hospital, Union Hospital, and
Zhongnan Hospital) and was dated March 8.3
However, there is still uncertainty as to whether patients
with IBD are more susceptible to COVID-19. To date, several
strategies have been introduced in China to better manage
patients with IBD during the Chinese outbreak of SARS-CoV2 (https://ecco-ibd.eu/images/6_Publication/6_8_Surveys/
2nd_Interview_COVID-19_ECCO_Taskforce_published.pdf).
The aim of this communication is to report the experience of our IBD center during the epidemic of SARS-CoV-2
in an area of high prevalence of the infection in Italy.
Link to resource
https://doi.org/10.1053/j.gastro.2020.03.062Collections
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