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dc.creatorSingh, Akriti
dc.creatorShaikh, Altamash
dc.creatorSingh, Ritu
dc.creatorKumar Singh, Awadhesh
dc.date.accessioned2020-07-23T19:28:18Z
dc.date.available2020-07-23T19:28:18Z
dc.date.created2020
dc.identifier.issn1871-4021spa
dc.identifier.otherhttps://doi.org/10.1016/j.dsx.2020.04.011spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/11059
dc.description.abstractBackground and aims: The last two decades have experienced the outbreaks of three different coronaviruses in the different parts of the world namely; Severe acute respiratory syndrome cornonavirus-1 (SARS-CoV-1), Middle East respiratory syndrome (MERS-CoV) and Severe acute respiratory syndrome cornonavirus-2 (SARS-CoV-2). We aimed to delineate the differences in viral dynamics and clinical features between them and tried to focus on every basic details of SARS-COV-2 (COVID-19) that every health care provider must know. Methods: We systematically searched the PubMed database up till April 2, 2020 and retrieved all the articles published on SARS-CoV-2, SARS-CoV-1, MERS-CoV that dealt with viral dynamics. Results: Ample data is available to suggest the differences in etiology, transmission cycle, diagnosis, genetics, hosts, reproductive rates, clinical features, laboratory diagnosis and radiological features between SARS-CoV-1, MERS-CoV and SARS-CoV-2. Conclusion: Although SARS-CoV-2 (COVID-19) is more infectious than SARS-CoV-1 and MERS-CoV, most infections are generally mild and self-limiting. However, case-fatality rates are very high in patients with COVID-19 with comorbidities, compared to SARS-CoV-1 and MERS-CoV.spa
dc.format.extent5 páginasspa
dc.format.mimetypeimage/jepgspa
dc.publisherClinical Research and Reviewseng
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectSARS-CoV-1spa
dc.subjectSARS-Co-V-2spa
dc.subjectMERSspa
dc.subjectCOVID-19spa
dc.subjectViral dynamicsspa
dc.titleCOVID-19: From bench to bed sidespa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.identifier.doihttps://doi.org/10.1016/j.dsx.2020.04.011spa


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