A human monoclonal antibody blocking SARS-CoV-2 infection
Date
2020-05-04Author
Wang, Chunyan
Li, Wentao
Drabek, Dubravka
Okba, Nisreen M.A.
van Haperen, Rien
Osterhaus, Albert D.M.E.
van Kuppeveld, Frank J.M.
Haagmans, Bart L.
Grosveld, Frank
Bosch, Berend Jan
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The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.
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https://www.nature.com/articles/s41467-020-16256-yCollections
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