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dc.creatorKayem, Gilles
dc.creatorLecarpentier, Edouard
dc.creatorDeruelle, Philippe
dc.creatorBretelle, Florence
dc.creatorAzria, Elie
dc.creatorBlanc, Julie
dc.creatorBohec, Caroline
dc.creatorBornes, Marie
dc.creatorCeccaldi, Pierre-François
dc.creatorChalet, Yasmine
dc.creatorChauleur, Céline
dc.creatorCordier, Anne-Gael
dc.creatorDesbrière, Raoul
dc.creatorDoret, Muriel
dc.creatorDreyfus, Michel
dc.creatorDriessen, Marine
dc.creatorFermaut, Marion
dc.creatorGallot, Denis
dc.creatorGarabédian, Charles
dc.creatorHuissoud, Cyril
dc.creatorLuton, Dominique
dc.creatorMorel, Olivier
dc.creatorPerrotin, Franck
dc.creatorPicone, Olivier
dc.creatorRozenberg, Patrick
dc.creatorSentilhes, Loïc
dc.creatorSroussi, Jeremy
dc.creatorVayssière, Christophe
dc.creatorVerspyck, Eric
dc.creatorVivanti, Alexandre J.
dc.creatorWiner, Norbert
dc.creatorAlessandrini, Vivien
dc.creatorSchmitz, Thomas
dc.date.accessioned2020-07-22T20:27:41Z
dc.date.available2020-07-22T20:27:41Z
dc.date.created2020
dc.identifier.issn2468-7847spa
dc.identifier.otherhttp://dx.doi.org/10.1016/j.jogoh.2020.101826spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/10979
dc.description.abstractObjective: To describe the course over time of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection in French women from the beginning of the pandemic until mid-April, the risk profile of women with respiratory complications, and short-term pregnancy outcomes. Methods: We collected a case series of pregnant womenwith COVID-19 in a research network of 33 French maternity units between March 1 and April 14, 2020. All cases of SARS-CoV-2 infection confirmed by a positive result on real-time reverse transcriptase polymerase chain reaction tests of a nasal sample and/ or diagnosed by a computed tomography chest scan were included and analyzed. The primary outcome measures were COVID-19 requiring oxygen (oxygen therapy or noninvasive ventilation) and critical COVID-19 (requiring invasive mechanical ventilation or extracorporeal membrane oxygenation, ECMO). Demographic data, baseline comorbidities, and pregnancy outcomes were also collected. Results: Active cases of COVID-19 increased exponentially during March 1–31, 2020; the numbers fell during April 1–14, after lockdown was imposed on March 17. The shape of the curve of active critical COVID-19 mirrored that of all active cases. By April 14, among the 617 pregnant women with COVID-19, 93 women (15.1 %; 95 %CI 12.3–18.1) had required oxygen therapy and 35 others (5.7 %; 95 %CI 4.0–7.8) had had a critical form of COVID-19. The severity of the disease was associated with age older than 35 years and obesity, as well as preexisting diabetes, previous preeclampsia, and gestational hypertension or preeclampsia. One woman with critical COVID-19 died (0.2 %; 95 %CI 0 0.9). Among the women who gave birth, rates of preterm birth in women with non-severe, oxygen-requiring, and critical COVID-19 were 13/123 (10.6 %), 14/29 (48.3 %), and 23/29 (79.3 %) before 37 weeks and 3/123 (2.4 %), 4/29 (13.8 %), and 14/29 (48.3 %) before 32 weeks, respectively. One neonate (0.5 %; 95 %CI 0.01–2.9) in the critical group died from prematurity. Conclusion: COVID-19 can be responsible for significant rates of severe acute, potentially deadly, respiratory distress syndromes. The most vulnerable pregnant women, those with comorbidities, may benefit particularly from prevention measures such as a lockdown.spa
dc.format.extent5 páginasspa
dc.format.mimetypeimage/jepgspa
dc.publisherScience Directeng
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCOVID 19spa
dc.subjectRespiratory complicationsspa
dc.subjectRisk factorsspa
dc.subjectLockdownspa
dc.titleA snapshot of the Covid-19 pandemic among pregnant women in Francespa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.identifier.doihttp://dx.doi.org/10.1016/j.jogoh.2020.101826spa


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