Antibody responses to SARS-CoV-2 in patients with COVID-19

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Date
2020-04-29
Author
Long, Quan Xin
Liu, Bai Zhong
Deng, Hai Jun
Wu, Gui Cheng
Deng, Kun
Chen, Yao Kai
Liao, Pu
Qiu, Jing Fu
Lin, Yong
Cai, Xue Fei
Wang, De Qiang
Hu, Yuan
Ren, Ji Hua
Tang, Ni
Xu, Yin Yin
Yu, Li Hua
Mo, Zhan
Gong, Fang
Zhang, Xiao Li
Tian, Wen Guang
Hu, Li
Zhang, Xian Xiang
Xiang, Jiang Lin
Du, Hong Xin
Liu, Hua Wen
Lang, Chun Hui
Luo, Xiao He
Wu, Shao Bo
Cui, Xiao Ping
Zhou, Zheng
Zhu, Man Man
Wang, Jing
Xue, Cheng Jun
Li, Xiao Feng
Wang, Li
Li, Zhi Jie
Wang, Kun
Niu, Chang Chun
Yang, Qing Jun
Tang, Xiao Jun
Zhang, Yong
Liu, Xia Mao
Li, Jin Jing
Zhang, De Chun
Zhang, Fan
Liu, Ping
Yuan, Jun
Li, Qin
Hu, Jie Li
Chen, Juan
Huang, Ai Long
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Summary in foreign language
We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG and IgM titers plateaued within 6 days after seroconversion. Serological testing may be helpful for the diagnosis of suspected patients with negative RT–PCR results and for the identification of asymptomatic infections.
URI
http://hdl.handle.net/20.500.12010/10809
Link to resource
https://www.nature.com/articles/s41591-020-0897-1#article-info
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