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dc.creatorYe, Feng
dc.creatorXu, Shicai
dc.creatorRong, Zhihua
dc.creatorXu, Ronghua
dc.creatorLiu, Xiaowei
dc.creatorDeng, Pingfu
dc.creatorLiu, Hai
dc.creatorXu, Xuejun
dc.date.accessioned2020-07-17T19:57:34Z
dc.date.available2020-07-17T19:57:34Z
dc.date.created2020
dc.identifier.issn1201-9712spa
dc.identifier.otherhttps://doi.org/10.1016/j.ijid.2020.03.042spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/10801
dc.description.abstractObjectives: With the ongoing outbreak of COVID-19 around the world, it has become a worldwide health concern. One previous study reported a family cluster with an asymptomatic transmission of COVID-19. Here, we report another series of cases and further demonstrate the repeatability of the transmission of COVID-19 by pre-symptomatic carriers. Methods: A familial cluster of five patients associated with COVID-19 was enrolled in the hospital. We collected epidemiological and clinical characteristics, laboratory outcomes from electronic medical records, and also verified them with the patients and their families. Results: Among them, three family members (Case 3/4/5) had returned from Wuhan. Additionally, two family members, those who had not traveled to Wuhan, also contracted COVID-19 after contacting with the other three family members. Case 1 developed severe pneumonia and was admitted to the ICU. Case 3 and Case 5 presented fever and cough on days two through three of hospitalization and had ground-glass opacity changes in their lungs. Case 4 presented with diarrhea and pharyngalgia after admission without radiographic abnormalities. Case 2 presented no clinical nor radiographic abnormalities. All five cases had an increasing level of C-reactive protein. Conclusions: Our findings indicate that COVID-19 can be transmitted by asymptomatic carriers during the incubation period.spa
dc.format.extent6 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.publisherScience Directeng
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCOVID-19spa
dc.subjectSARS-CoV-2spa
dc.subjectPneumoniaspa
dc.subjectIncubation periodspa
dc.subjectAsymptomatic carrierspa
dc.titleDelivery of infection from asymptomatic carriers of COVID-19 in a familial clusterspa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.identifier.doihttps://doi.org/10.1016/j.ijid.2020.03.042spa


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