Show simple item record

dc.coverage.spatialColombiaspa
dc.creatorLiang, Yujie
dc.creatorXu, Jiabin
dc.creatorChu, Mei
dc.creatorMai, Jianbo
dc.creatorLai, Niangmei
dc.creatorTang, Wen
dc.creatorYang, Tuanjie
dc.creatorZhang, Sien
dc.creatorGuan, Chenyu
dc.creatorZhong, Fan
dc.creatorYang, Liuping
dc.creatorLiao, Guiqing
dc.date.accessioned2020-07-09T17:08:12Z
dc.date.available2020-07-09T17:08:12Z
dc.date.created2020
dc.identifier.otherhttps://doi.org/10.1016/j.ijid.2020.06.086spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/10375
dc.description.abstractObjectives To detailly described the neurosensory dysfunction, including hyposmia, hypogeusia and tinnitus, in patients with COVID-19. Methods Clinical characteristics and oropharyngeal swabs were obtained from 86 patients with COVID-19 hospitalized in Guangzhou Eighth People’s Hospital. Chronological analysis method was used to detailly clarify the neurosensory dysfunction. The cycle threshold (Ct) values were used to approximately indicate viral load. Results Forth-four (51.2%) patients had neurosensory dysfunction: hyposmia (34, 39.5%), hypogeusia (33, 38.4%), and tinnitus (3, 3.5%). Neurosensory dysfunction was significantly more common in patients under 40 years old (p=0.001) or women (p=0.006). Hyposmia and hypogeusia coexisted in 23 (26.7%) patients. The interval between onset of hyposmia and hypogeusia was 0.7±1.46 days. The interval from onset of hyposmia and hypogeusia to typical symptoms was 0.22±4.57 and 0.75±6.77 days; the interval from onset of hyposmia and hypogeusia to admission was 6.06±6.68 and 5.76±7.68 days; and the duration of hyposmia and hypogeusia was 9.09±5.74 and 7.12±4.66 days, respectively. The viral load was high since symptoms onset, peaked within the first week, and then gradually declined. Conclusions The neurosensory dysfunction tends to occur in the early stage of COVID-19, and it could be used as a marker for early diagnosis of COVID-19spa
dc.format.extent20 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.publisherBogotá : Universidad de Bogotá Jorge Tadeo Lozano, 2020spa
dc.subjectNeurosensory dysfunctionspa
dc.subjectCOVID-19spa
dc.subjectHyposmiaspa
dc.subjectHypogeusiaspa
dc.subjectDiagnosisspa
dc.titleNeurosensory dysfunction: a diagnostic marker of early COVID-19spa
dc.type.localArtículospa
dc.subject.lembCOVID-19 (Enfermedad) - Diagnósticospa
dc.subject.lembCOVID-19 (Enfermedad) -- Investigacionesspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAbierto (Texto Completo)spa
dc.identifier.repourlhttp://expeditiorepositorio.utadeo.edu.cospa
dc.identifier.doi: https://doi.org/10.1016/j.ijid.2020.06.086spa
dc.format.rda1 recurso en línea (archivo de texto)spa
dc.type.driverinfo:eu-repo/semantics/articlespa


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record