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A review of therapeutic agents and Chinese herbal medicines against SARS-COV-2 (COVID-19)

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dc.creatorHuang, Fangfang
dc.creatorLi, Ying
dc.creatorLeung, Elaine Lai Han
dc.creatorLiu, Xiaohua
dc.creatorLiu, Kaifeng
dc.creatorWang, Qu
dc.creatorLan, Yongqi
dc.creatorLi, Xiaoling
dc.creatorYu, Haibing
dc.creatorCui, Liao
dc.creatorLuo, Hui
dc.creatorLuo, Lianxiang
dc.date.accessioned2020-08-06T16:58:16Z
dc.date.available2020-08-06T16:58:16Z
dc.date.created2020-08
dc.description.abstractenglishThe epidemic of pneumonia (COVID-19) caused by novel coronavirus (SARS-CoV-2) infection has been listed as a public health emergency of international concern by the World Health Organization (WHO), and its harm degree is defined as a global “pandemic”. At present, the efforts of various countries focus on the rapid diagnosis and isolation of patients, as well as to find a treatment that can combat the most serious impact of the disease. The number of reported COVID-19 virus infections is still increasing. Unfortunately, no drugs or vaccines have been approved for the treatment of human coronaviruses, but there is an urgent need for in-depth research on emerging human infectious coronaviruses. Clarification transmission routes and pathogenic mechanisms, and identification of potential drug treatment targets will promote the development of effective prevention and treatment measures. In the absence of confirmed effective treatments, due to public health emergencies, it is essential to study the possible effects of existing approved antivirals drugs or Chinese herbal medicines for SARS-CoV-2. This review summarizes the epidemiological characteristics, pathogenesis, virus structure and targeting strategies of COVID-19. Meanwhile, this review also focus on the re-purposing of clinically approved drugs and Chinese herbal medicines that may be used to treat COVID-19 and provide new ideas for the discovery of small molecular compounds with potential therapeutic effects on novel COVID-19.spa
dc.format.extent12 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1016/j.phrs.2020.104929spa
dc.identifier.issn1043-6618spa
dc.identifier.otherhttps://www.sciencedirect.com/science/article/pii/S1043661820312378?via%3Dihubspa
dc.identifier.urihttps://hdl.handle.net/20.500.12010/11688
dc.publisherScience Directeng
dc.publisherPharmacological Researchspa
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.rights.localAcceso restringidospa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectNeumoníaspa
dc.subjectAgentes terapéuticosspa
dc.subjectHierbas medicinales chinasspa
dc.subject.keywordPneumoniaspa
dc.subject.keywordTherapeutic agentsspa
dc.subject.keywordChinese herbal medicinesspa
dc.subject.keywordTreatmentspa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.titleA review of therapeutic agents and Chinese herbal medicines against SARS-COV-2 (COVID-19)spa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localArtículospa
dspace.entity.typePublication

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