The contribution is an introduction to a new trend in the assessment of buildings as concerns their fire safety, and namely assessing the refrigerating system with refrigerants as such, forming an important part of the technological equipment of the edifice. Down to the present day both refrigerants and refrigerating systems used to be in the background of considerations, being handled as mere component parts of the ventilation systems, or even totally left out of consideration in fire safety statements relating to buildings. However, a certain improvement is seen to have set in, thanks to which refrigerants are claiming due attention. The reason for focusing upon their problems lies in the fact that refrigerants with high GWP index are being gradually replaced with low GWP index preparations ever since 2015, and namely due to the legitimate requirement of environmental protection. High GWP index refrigerants are even going to be prohibited after 2020. The shady side of this process is the considerable flammability of the newly introduced refrigerants. This is also why these problems arouse increased interest in the domain of the fire safety experts of the building trade on the one hand side, and among those specialized in refrigerating systems on the other hand side. This paper offers an outline of ways helping to solve the situation having set in. The aim of the paper is to point out the new situation in buildings where there are refrigerating systems with flammable refrigerants and the necessary measures resulting from the given situation, such as reducing the amount of refrigerant and the need to ventilate the space using cooling.